When Do Microbes Stimulate Rheumatoid Factor?

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When Do Microbes Stimulate Rheumatoid Factor?

A nti– ␥-globulins or rheumatoid factors (RF) were first described in the early 1940s. They are present in Ͼ 70% of patients with rheumatoid arthritis (RA) and high titers are associated with severe disease, but they also appear in a large number of other diseases including viral, bacterial, and parasitic infections (1). In spite of their wide spread occurrence , it is still a puzzle how or why...

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Commentary When Do Microbes Stimulate Rheumatoid Factor ?

A nti– ␥-globulins or rheumatoid factors (RF) were first described in the early 1940s. They are present in Ͼ 70% of patients with rheumatoid arthritis (RA) and high titers are associated with severe disease, but they also appear in a large number of other diseases including viral, bacterial, and parasitic infections (1). In spite of their wide spread occurrence , it is still a puzzle how or why...

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ژورنال

عنوان ژورنال: Journal of Experimental Medicine

سال: 1997

ISSN: 0022-1007,1540-9538

DOI: 10.1084/jem.185.10.1721